Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

BACKGROUND: Immune cell trafficking into the CNS is considered to contribute to pathogenesis in MS and its animal model, EAE. Disruption of the blood–brain barrier (BBB) is a hallmark of these pathologies and a potential target of therapeutics. Human embryonic stem cell-derived mesenchymal stem/stro...

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Detalles Bibliográficos
Autores principales: Ge, Shujun, Jiang, Xi, Paul, Debayon, Song, Li, Wang, Xiaofang, Pachter, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600885/
https://www.ncbi.nlm.nih.gov/pubmed/31256757
http://dx.doi.org/10.1186/s12987-019-0138-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600885/
https://www.ncbi.nlm.nih.gov/pubmed/31256757
http://dx.doi.org/10.1186/s12987-019-0138-5

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