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Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model

BACKGROUND: Immune cell trafficking into the CNS is considered to contribute to pathogenesis in MS and its animal model, EAE. Disruption of the blood–brain barrier (BBB) is a hallmark of these pathologies and a potential target of therapeutics. Human embryonic stem cell-derived mesenchymal stem/stro...

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Detalles Bibliográficos
Autores principales:	Ge, Shujun, Jiang, Xi, Paul, Debayon, Song, Li, Wang, Xiaofang, Pachter, Joel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600885/ https://www.ncbi.nlm.nih.gov/pubmed/31256757 http://dx.doi.org/10.1186/s12987-019-0138-5

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