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Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype
Artificially selected model organisms can reveal hidden features of the genetic architecture of the complex disorders that they model. Addictions are disease phenotypes caused by different intermediate phenotypes and pathways and thereby are potentially highly polygenic. High responder (bHR) and low...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600920/ https://www.ncbi.nlm.nih.gov/pubmed/31182603 http://dx.doi.org/10.1073/pnas.1820410116 |