Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice

Iron deficiency augments hypoxic pulmonary arterial pressure in healthy individuals and exacerbates pulmonary arterial hypertension (PAH) in patients, even without anemia. Conversely, iron supplementation has been shown to be beneficial in both settings. The mechanisms underlying the effects of iron...

Descripción completa

Detalles Bibliográficos
Autores principales: Lakhal-Littleton, Samira, Crosby, Alexi, Frise, Matthew C., Mohammad, Goran, Carr, Carolyn A., Loick, Paul A. M., Robbins, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600981/
https://www.ncbi.nlm.nih.gov/pubmed/31152133
http://dx.doi.org/10.1073/pnas.1822010116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600981/
https://www.ncbi.nlm.nih.gov/pubmed/31152133
http://dx.doi.org/10.1073/pnas.1822010116

Ejemplares similares