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Relationship between porcine miR-20a and its putative target low-density lipoprotein receptor based on dual luciferase reporter gene assays

OBJECTIVE: Mutations in low-density lipoprotein receptor (LDLR), which encodes a critical protein for cholesterol homeostasis and lipid metabolism in mammals, are involved in cardiometabolic diseases, such as familial hypercholesterolemia in pigs. Whereas microRNAs (miRNAs) can control LDLR regulati...

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Detalles Bibliográficos
Autores principales: Ding, Yueyun, Zhu, Shujiao, Wu, Chaodong, Qian, Li, Li, DengTao, Wang, Li, Wang, Yuanlang, Zhang, Wei, Yang, Min, Ding, Jian, Wu, Xudong, Zhang, Xiaodong, Gao, Yafei, Yin, Zongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601058/
https://www.ncbi.nlm.nih.gov/pubmed/30744358
http://dx.doi.org/10.5713/ajas.18.0510