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Relationship between porcine miR-20a and its putative target low-density lipoprotein receptor based on dual luciferase reporter gene assays
OBJECTIVE: Mutations in low-density lipoprotein receptor (LDLR), which encodes a critical protein for cholesterol homeostasis and lipid metabolism in mammals, are involved in cardiometabolic diseases, such as familial hypercholesterolemia in pigs. Whereas microRNAs (miRNAs) can control LDLR regulati...
Autores principales: | Ding, Yueyun, Zhu, Shujiao, Wu, Chaodong, Qian, Li, Li, DengTao, Wang, Li, Wang, Yuanlang, Zhang, Wei, Yang, Min, Ding, Jian, Wu, Xudong, Zhang, Xiaodong, Gao, Yafei, Yin, Zongjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST)
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601058/ https://www.ncbi.nlm.nih.gov/pubmed/30744358 http://dx.doi.org/10.5713/ajas.18.0510 |
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