Mechanisms of thrombocytopenia in platelet-type von Willebrand disease

Platelet-type von Willebrand disease is an inherited platelet disorder characterized by thrombocytopenia with large platelets caused by gain-of-function variants in GP1BA leading to enhanced GPIbα-von Willebrand factor (vWF) interaction. GPIbα and vWF play a role in megakaryocytopoiesis, thus we aim...

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Detalles Bibliográficos
Autores principales: Bury, Loredana, Malara, Alessandro, Momi, Stefania, Petito, Eleonora, Balduini, Alessandra, Gresele, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601082/
https://www.ncbi.nlm.nih.gov/pubmed/30655369
http://dx.doi.org/10.3324/haematol.2018.200378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601082/
https://www.ncbi.nlm.nih.gov/pubmed/30655369
http://dx.doi.org/10.3324/haematol.2018.200378

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