Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death

Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphomas are tumors that carry translocations involving the ALK gene at the 2p23 locus, leading to the expression of ALK tyrosine kinase fusion oncoproteins. Amongst hematologic malignancies, these lymphomas are particular in that they...

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Detalles Bibliográficos
Autores principales: Torossian, Avedis, Broin, Nicolas, Frentzel, Julie, Daugrois, Camille, Gandarillas, Sarah, Saati, Talal Al, Lamant, Laurence, Brousset, Pierre, Giuriato, Sylvie, Espinos, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601090/
https://www.ncbi.nlm.nih.gov/pubmed/30679328
http://dx.doi.org/10.3324/haematol.2017.181966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601090/
https://www.ncbi.nlm.nih.gov/pubmed/30679328
http://dx.doi.org/10.3324/haematol.2017.181966

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