ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

OBJECTIVE: Insulin suppresses adipose tissue lipolysis after a meal, playing a key role in metabolic homeostasis. This is mediated via the kinase Akt and its substrate phosphodiesterase 3B (PDE3B). Once phosphorylated and activated, PDE3B hydrolyses cAMP leading to the inactivation of cAMP-dependent...

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Detalles Bibliográficos
Autores principales: Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601125/
https://www.ncbi.nlm.nih.gov/pubmed/31105056
http://dx.doi.org/10.1016/j.molmet.2019.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601125/
https://www.ncbi.nlm.nih.gov/pubmed/31105056
http://dx.doi.org/10.1016/j.molmet.2019.05.002

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