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Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C
Natural killer (NK) cells have an important role in immune defense against viruses and cancer. Activation of human NK cell cytotoxicity toward infected or tumor cells is regulated by killer cell immunoglobulin-like receptors (KIRs) that bind to human leukocyte antigen class I (HLA-I). Combinations o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601252/ https://www.ncbi.nlm.nih.gov/pubmed/31138701 http://dx.doi.org/10.1073/pnas.1903781116 |