Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism

In cirrhosis, liver microvascular dysfunction is a key factor increasing hepatic vascular resistance to portal blood flow, which leads to portal hypertension. De‐regulated inflammatory and pro‐apoptotic processes due to chronic injury play important roles in the dysfunction of liver sinusoidal cells...

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Detalles Bibliográficos
Autores principales: Gracia‐Sancho, Jordi, Manicardi, Nicolò, Ortega‐Ribera, Martí, Maeso‐Díaz, Raquel, Guixé‐Muntet, Sergi, Fernández‐Iglesias, Anabel, Hide, Diana, García‐Calderó, Héctor, Boyer‐Díaz, Zoe, Contreras, Patricia C., Spada, Alfred, Bosch, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601324/
https://www.ncbi.nlm.nih.gov/pubmed/31304452
http://dx.doi.org/10.1002/hep4.1360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601324/
https://www.ncbi.nlm.nih.gov/pubmed/31304452
http://dx.doi.org/10.1002/hep4.1360

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