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OLFM4 Enhances STAT3 Activation and Promotes Tumor Progression by Inhibiting GRIM19 Expression in Human Hepatocellular Carcinoma

Olfactomedin 4 (OLFM4) induces signal transducer and activator of transcription 3 (STAT3) activation by inhibiting gene associated with retinoid‐interferon‐induced mortality 19 (GRIM19), a strong STAT3 suppressor gene; however, the mechanisms of OLFM4 for regulating GRIM19‐STAT3 cascade in hepatocel...

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Detalles Bibliográficos
Autores principales: Ashizawa, Yosuke, Kuboki, Satoshi, Nojima, Hiroyuki, Yoshitomi, Hideyuki, Furukawa, Katsunori, Takayashiki, Tsukasa, Takano, Shigetsugu, Miyazaki, Masaru, Ohtsuka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601327/
https://www.ncbi.nlm.nih.gov/pubmed/31304451
http://dx.doi.org/10.1002/hep4.1361