Determinants for Neoantigen Identification

All tumors accumulate genetic alterations, some of which can give rise to mutated, non-self peptides presented by human leukocyte antigen (HLA) molecules and elicit T-cell responses. These immunogenic mutated peptides, or neoantigens, are foreign in nature and display exquisite tumor specificity. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Garcia-Garijo, Andrea, Fajardo, Carlos Alberto, Gros, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601353/
https://www.ncbi.nlm.nih.gov/pubmed/31293573
http://dx.doi.org/10.3389/fimmu.2019.01392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601353/
https://www.ncbi.nlm.nih.gov/pubmed/31293573
http://dx.doi.org/10.3389/fimmu.2019.01392

Ejemplares similares