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Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery

The Piwi-interacting RNA (piRNA) pathway is a small RNA-based immune system that silences mobile genetic elements in animal germlines. piRNA biogenesis requires a specialized machinery that converts long single-stranded precursors into small RNAs of ∼25-nucleotides in length. This process involves f...

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Detalles Bibliográficos
Autores principales: Munafò, Marzia, Manelli, Vera, Falconio, Federica A., Sawle, Ashley, Kneuss, Emma, Eastwood, Evelyn L., Seah, Jun Wen Eugene, Czech, Benjamin, Hannon, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601507/
https://www.ncbi.nlm.nih.gov/pubmed/31123065
http://dx.doi.org/10.1101/gad.325662.119