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Important roles of CD32 in promoting suppression of IL-4 induced immune responses by a novel anti-IL-4Rα therapeutic antibody

Asthma is characterized by airway hyperresponsiveness and inflammation, as well as underlying structural changes to the airways. Interleukin-4 (IL-4) is a key T-helper type 2 (Th2) cytokine that plays important roles in the pathogenesis of atopic and eosinophilic asthma. We developed a novel humaniz...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Jiang, Liangfeng, Deng, Lan, Xu, Wei, Cao, Yang, Chen, Chen, Yang, Yan, Wu, Huiling, Huang, Yuping, Zhu, Zhenping, Huang, Haomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601543/
https://www.ncbi.nlm.nih.gov/pubmed/30950681
http://dx.doi.org/10.1080/19420862.2019.1601985