Sirtuin 3 promotes microglia migration by upregulating CX3CR1

We studied the role of Sirtuin 3 (SIRT3) in microglial cell migration in ischemic stroke. We used a middle cerebral artery occlusion (MCAO) model of focal ischemia. We then applied lentivirus-packaged SIRT3 overexpression and knock down in microglial N9 cells to investigate the underlying mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Runjing, Li, Shiping, Yin, Junxiang, Guo, Li, Shi, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601551/
https://www.ncbi.nlm.nih.gov/pubmed/31208274
http://dx.doi.org/10.1080/19336918.2019.1629224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601551/
https://www.ncbi.nlm.nih.gov/pubmed/31208274
http://dx.doi.org/10.1080/19336918.2019.1629224

Ejemplares similares