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Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer

Our previous studies have demonstrated that XIAP promotes bladder cancer metastasis through upregulating RhoGDIβ/MMP-2 pathway. However, the molecular mechanisms leading to the XIAP upregulation was unclear. In current studies, we found that XIAP was overexpressed in human high grade BCs, high metas...

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Detalles Bibliográficos
Autores principales: Jin, Honglei, Xue, Lei, Mo, Lan, Zhang, Dongyun, Guo, Xirui, Xu, Jiheng, Li, Jingxia, Peng, Minggang, Zhao, Xuewei, Zhong, Minghao, Xu, Dazhong, Wu, Xue-Ru, Huang, Haishan, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601559/
https://www.ncbi.nlm.nih.gov/pubmed/31240993
http://dx.doi.org/10.1080/19336918.2019.1633851