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KMT2A histone methyltransferase contributes to colorectal cancer development by promoting cathepsin Z transcriptional activation

Accumulating evidence supports the notion that epigenetic modifiers are abnormal in carcinogenesis and have a fundamental role in cancer progression. Among these aberrant epigenetic modifiers, the function of histone methyltransferase KMT2A in somatic tumors is not well known. By analyzing KMT2A exp...

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Detalles Bibliográficos
Autores principales: Fang, Yang, Zhang, Dan, Hu, Tingting, Zhao, Hongyan, Zhao, Xuan, Lou, Zhefeng, He, Yongshan, Qin, Wenzheng, Xia, Jianfu, Zhang, Xiaohua, Ye, Le‐chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601586/
https://www.ncbi.nlm.nih.gov/pubmed/31090199
http://dx.doi.org/10.1002/cam4.2226