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MicroRNA‐4286 promotes cell proliferation, migration, and invasion via PTEN regulation of the PI3K/Akt pathway in non‐small cell lung cancer

It is well‐known that phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor which negatively regulates PI3K/AKT signaling and is activated widely in non‐small cell lung cancers (NSCLC). However, genetic alterations in PTEN genes are rare, suggesting an undefined mech...

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Detalles Bibliográficos
Autores principales: Ling, Chunhua, Wang, Xueting, Zhu, Jianjie, Tang, Haicheng, Du, Wenwen, Zeng, Yuanyuan, Sun, Lin, Huang, Jian‐An, Liu, Zeyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601592/
https://www.ncbi.nlm.nih.gov/pubmed/31074594
http://dx.doi.org/10.1002/cam4.2220