Metformin and 4SC‐202 synergistically promote intrinsic cell apoptosis by accelerating ΔNp63 ubiquitination and degradation in oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is the most common and aggressive epithelial tumor in the head and neck region with a rising incidence. Despite the advances in basic science and clinical research, the overall survival rate of OSCC remains low. Thus finding novel effective therapeutic agents for...

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Detalles Bibliográficos
Autores principales: He, Yuan, Tai, Shanshan, Deng, Miao, Fan, Zhaona, Ping, Fan, He, Lihong, Zhang, Chi, Huang, Yulei, Cheng, Bin, Xia, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601594/
https://www.ncbi.nlm.nih.gov/pubmed/31025540
http://dx.doi.org/10.1002/cam4.2206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601594/
https://www.ncbi.nlm.nih.gov/pubmed/31025540
http://dx.doi.org/10.1002/cam4.2206

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