Phosphocreatine attenuates Gynura segetum-induced hepatocyte apoptosis via a SIRT3-SOD2-mitochondrial reactive oxygen species pathway

Purpose: To investigate the mitochondria-related mechanism of Gynura segetum (GS)-induced apoptosis and the protective effect of phosphocreatine (PCr), a mitochondrial respiration regulator. Methods: First, the mechanism was explored in human hepatocyte cell line. The mitochondrial oxidative stress...

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Detalles Bibliográficos
Autores principales: Li, Dong-Ping, Chen, Ying-Ling, Jiang, Hong-Yue, Chen, Yun, Zeng, Xiao-Qing, Xu, Li-Li, Ye, Yang, Ke, Chang-Qiang, Lin, Ge, Wang, Ji-Yao, Gao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602055/
https://www.ncbi.nlm.nih.gov/pubmed/31417240
http://dx.doi.org/10.2147/DDDT.S203564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602055/
https://www.ncbi.nlm.nih.gov/pubmed/31417240
http://dx.doi.org/10.2147/DDDT.S203564

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