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Are Hydroethidine-Based Probes Reliable for Reactive Oxygen Species Detection?

Detection and quantification of the highly reactive and short-lived superoxide (O(•)(2)(−)) can be challenging. Here, we present a new mass spectrometry (MS)-based method to detect and quantify O(•)(2)(−) using three fluorogenic hydroethidine probes: hydroethidine (HE), mito-hydroethidine (mito-HE),...

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Detalles Bibliográficos
Autores principales: Xiao, Yi, Meierhofer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602104/
https://www.ncbi.nlm.nih.gov/pubmed/29790367
http://dx.doi.org/10.1089/ars.2018.7535