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Quantitative Analyses of the Yeast Oxidative Protein Folding Pathway In Vitro and In Vivo

Aims: Efficient oxidative protein folding (OPF) in the endoplasmic reticulum (ER) is a key requirement of the eukaryotic secretory pathway. In particular, protein folding linked to the formation of disulfide bonds, an activity dependent on the enzyme protein disulfide isomerase (PDI), is crucial. Fo...

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Detalles Bibliográficos
Autores principales: Beal, Dave M., Bastow, Emma L., Staniforth, Gemma L., von der Haar, Tobias, Freedman, Robert B., Tuite, Mick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602113/
https://www.ncbi.nlm.nih.gov/pubmed/30880408
http://dx.doi.org/10.1089/ars.2018.7615