Discoidin Domain Receptor 1 (DDR1) tyrosine kinase is upregulated in PKD kidneys but does not play a role in the pathogenesis of polycystic kidney disease

Tolvaptan is the only drug approved to slow cyst growth and preserve kidney function in patients with autosomal dominant polycystic kidney disease (ADPKD). However, its limited efficacy combined with significant side effects underscores the need to identify new and safe therapeutic drug targets to s...

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Detalles Bibliográficos
Autores principales: Soomro, Irfana, Hong, Aram, Li, Zhai, Duncan, James S., Skolnik, Edward Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602183/
https://www.ncbi.nlm.nih.gov/pubmed/31260458
http://dx.doi.org/10.1371/journal.pone.0211670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602183/
https://www.ncbi.nlm.nih.gov/pubmed/31260458
http://dx.doi.org/10.1371/journal.pone.0211670

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