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Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution

BACKGROUND: Pathogenic treponemes related to Treponema pallidum are both human (causing syphilis, yaws, bejel) and animal pathogens (infections of primates, venereal spirochetosis in rabbits). A set of 11 treponemal genome sequences including those of five Treponema pallidum ssp. pallidum (TPA) stra...

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Detalles Bibliográficos
Autores principales: Maděránková, Denisa, Mikalová, Lenka, Strouhal, Michal, Vadják, Šimon, Kuklová, Ivana, Pospíšilová, Petra, Krbková, Lenka, Koščová, Pavlína, Provazník, Ivo, Šmajs, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602244/
https://www.ncbi.nlm.nih.gov/pubmed/31216284
http://dx.doi.org/10.1371/journal.pntd.0007463