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Cyclophilin B control of lysine post-translational modifications of skin type I collagen

Covalent intermolecular cross-linking of collagen is essential for tissue stability. Recent studies have demonstrated that cyclophilin B (CypB), an endoplasmic reticulum (ER)-resident peptidyl-prolyl cis-trans isomerase, modulates lysine (Lys) hydroxylation of type I collagen impacting cross-linking...

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Detalles Bibliográficos
Autores principales: Terajima, Masahiko, Taga, Yuki, Cabral, Wayne A., Liu, Ying, Nagasawa, Masako, Sumida, Noriko, Kayashima, Yukako, Chandrasekaran, Prashant, Han, Lin, Maeda, Nobuyo, Perdivara, Irina, Hattori, Shunji, Marini, Joan C., Yamauchi, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602281/
https://www.ncbi.nlm.nih.gov/pubmed/31173582
http://dx.doi.org/10.1371/journal.pgen.1008196