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Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis

BACKGROUND: Leishmania parasites are transmitted to vertebrate hosts by phlebotomine sandflies and, in humans, may cause tegumentary or visceral leishmaniasis. The role of PKR (dsRNA activated kinase) and Toll-like receptor 3 (TLR3) activation in the control of Leishmania infection highlights the im...

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Detalles Bibliográficos
Autores principales: Rath, Carolina Torturella, Schnellrath, Laila Castro, Damaso, Clarissa R., de Arruda, Luciana Barros, Vasconcelos, Pedro Fernando da Costa, Gomes, Claudia, Laurenti, Marcia Dalastra, Calegari Silva, Teresa Cristina, Vivarini, Áislan de Carvalho, Fasel, Nicolas, Pereira, Renata Meirelles Santos, Lopes, Ulisses Gazos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602282/
https://www.ncbi.nlm.nih.gov/pubmed/31216268
http://dx.doi.org/10.1371/journal.pntd.0007500