Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity

LAG1 was the first longevity assurance gene discovered in Saccharomyces cerevisiae. The Lag1 protein is a ceramide synthase and its homolog, Lac1, has a similar enzymatic function but no role in aging. Lag1 and Lac1 lie in an enzymatic branch point of the sphingolipid pathway that is interconnected...

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Detalles Bibliográficos
Autores principales: Megyeri, Márton, Prasad, Rupali, Volpert, Giora, Sliwa-Gonzalez, Andrzej, Haribowo, A. Galih, Aguilera-Romero, Auxiliadora, Riezman, Howard, Barral, Yves, Futerman, Anthony H., Schuldiner, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602303/
https://www.ncbi.nlm.nih.gov/pubmed/31164445
http://dx.doi.org/10.1242/jcs.228411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602303/
https://www.ncbi.nlm.nih.gov/pubmed/31164445
http://dx.doi.org/10.1242/jcs.228411

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