α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency

AIM: It has been indicated that NPs may change the amyloidogenic steps of proteins and relevant cytotoxicity. Therefore, this report assigned to explore the impact of ZVFe NPs on the amyloidogenicity and cytotoxicity of α-synuclein as one of the many known amyloid proteins. METHODS: The characteriza...

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Detalles Bibliográficos
Autores principales: Tahaei Gilan, Seyedeh Sahar, Yahya Rayat, Dorsa, Mustafa, Twana Ahmed, Aziz, Falah Mohammad, Shahpasand, Koorosh, Akhtari, Keivan, Salihi, Abbas, Abou-Zied, Osama K, Falahati, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602305/
https://www.ncbi.nlm.nih.gov/pubmed/31417259
http://dx.doi.org/10.2147/IJN.S212387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602305/
https://www.ncbi.nlm.nih.gov/pubmed/31417259
http://dx.doi.org/10.2147/IJN.S212387

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