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α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency
AIM: It has been indicated that NPs may change the amyloidogenic steps of proteins and relevant cytotoxicity. Therefore, this report assigned to explore the impact of ZVFe NPs on the amyloidogenicity and cytotoxicity of α-synuclein as one of the many known amyloid proteins. METHODS: The characteriza...
Autores principales: | Tahaei Gilan, Seyedeh Sahar, Yahya Rayat, Dorsa, Mustafa, Twana Ahmed, Aziz, Falah Mohammad, Shahpasand, Koorosh, Akhtari, Keivan, Salihi, Abbas, Abou-Zied, Osama K, Falahati, Mojtaba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602305/ https://www.ncbi.nlm.nih.gov/pubmed/31417259 http://dx.doi.org/10.2147/IJN.S212387 |
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