Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing

Global inhibition of N-linked glycosylation broadly reduces glycan occupancy on glycoproteins, but identifying how this inhibition functionally impacts specific glycoproteins is challenging. This limits our understanding of pathogenesis in the congenital disorders of glycosylation (CDG). We used sel...

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Detalles Bibliográficos
Autores principales: Klaver, Elsenoor, Zhao, Peng, May, Melanie, Flanagan-Steet, Heather, Freeze, Hudson H., Gilmore, Reid, Wells, Lance, Contessa, Joseph, Steet, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602306/
https://www.ncbi.nlm.nih.gov/pubmed/31101650
http://dx.doi.org/10.1242/dmm.039602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602306/
https://www.ncbi.nlm.nih.gov/pubmed/31101650
http://dx.doi.org/10.1242/dmm.039602

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