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Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing
Global inhibition of N-linked glycosylation broadly reduces glycan occupancy on glycoproteins, but identifying how this inhibition functionally impacts specific glycoproteins is challenging. This limits our understanding of pathogenesis in the congenital disorders of glycosylation (CDG). We used sel...
Autores principales: | Klaver, Elsenoor, Zhao, Peng, May, Melanie, Flanagan-Steet, Heather, Freeze, Hudson H., Gilmore, Reid, Wells, Lance, Contessa, Joseph, Steet, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602306/ https://www.ncbi.nlm.nih.gov/pubmed/31101650 http://dx.doi.org/10.1242/dmm.039602 |
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