Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation

Congenital heart defects affect ∼2% of live births and often involve malformations of the semilunar (aortic and pulmonic) valves. We previously reported a highly penetrant GATA4 p.Gly296Ser mutation in familial, congenital atrial septal defects and pulmonic valve stenosis and showed that mice harbor...

Descripción completa

Detalles Bibliográficos
Autores principales: LaHaye, Stephanie, Majumdar, Uddalak, Yasuhara, Jun, Koenig, Sara N., Matos-Nieves, Adrianna, Kumar, Rahul, Garg, Vidu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602309/
https://www.ncbi.nlm.nih.gov/pubmed/31138536
http://dx.doi.org/10.1242/dmm.036764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602309/
https://www.ncbi.nlm.nih.gov/pubmed/31138536
http://dx.doi.org/10.1242/dmm.036764

Ejemplares similares