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Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism

The ventricular-subventricular zone (V-SVZ) of the forebrain is the source of neurogenic stem/precursor cells for adaptive and homeostatic needs throughout the life of most mammals. Here, we report that Suppressor of Fused (Sufu) plays a critical role in the establishment of the V-SVZ at early neona...

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Detalles Bibliográficos
Autores principales: Gomez, Hector G., Noguchi, Hirofumi, Castillo, Jesse Garcia, Aguilar, David, Pleasure, Samuel J., Yabut, Odessa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602331/
https://www.ncbi.nlm.nih.gov/pubmed/31142467
http://dx.doi.org/10.1242/bio.039248