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Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue

Autism spectrum disorder (ASD) encompasses a collection of complex neuropsychiatric disorders characterized by deficits in social functioning, communication and repetitive behaviour. Building on recent studies supporting a role for developmentally moderated regulatory genomic variation in the molecu...

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Detalles Bibliográficos
Autores principales: Wong, Chloe C Y, Smith, Rebecca G, Hannon, Eilis, Ramaswami, Gokul, Parikshak, Neelroop N, Assary, Elham, Troakes, Claire, Poschmann, Jeremie, Schalkwyk, Leonard C, Sun, Wenjie, Prabhakar, Shyam, Geschwind, Daniel H, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602383/
https://www.ncbi.nlm.nih.gov/pubmed/31220268
http://dx.doi.org/10.1093/hmg/ddz052