An one-pot two-step automated synthesis of [(18)F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans

[(18)F]T807 is a potent tau protein imaging agent. In order to fulfill the demand from preclinical and clinical studies, we developed an automated one-pot two-step synthesis of this potent tau imaging agent and studied its stability, and dosimetry in mice and monkeys. We also conducted a preliminary...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Yao, Chiu, Ming-Jang, Yen, Ruoh-Fang, Tsai, Chia-Ling, Hsieh, Hao-Yu, Chiu, Ching-Hung, Wu, Chi-Han, Hsin, Ling-Wei, Tzen, Kai-Yuan, Cheng, Cheng-Yi, Ma, Kuo-Hsing, Shiue, Chyng-Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602418/
https://www.ncbi.nlm.nih.gov/pubmed/31260447
http://dx.doi.org/10.1371/journal.pone.0217384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602418/
https://www.ncbi.nlm.nih.gov/pubmed/31260447
http://dx.doi.org/10.1371/journal.pone.0217384

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