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An one-pot two-step automated synthesis of [(18)F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
[(18)F]T807 is a potent tau protein imaging agent. In order to fulfill the demand from preclinical and clinical studies, we developed an automated one-pot two-step synthesis of this potent tau imaging agent and studied its stability, and dosimetry in mice and monkeys. We also conducted a preliminary...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602418/ https://www.ncbi.nlm.nih.gov/pubmed/31260447 http://dx.doi.org/10.1371/journal.pone.0217384 |