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Drug ReposER: a web server for predicting similar amino acid arrangements to known drug binding interfaces for potential drug repositioning

A common drug repositioning strategy is the re-application of an existing drug to address alternative targets. A crucial aspect to enable such repurposing is that the drug's binding site on the original target is similar to that on the alternative target. Based on the assumption that proteins w...

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Detalles Bibliográficos
Autores principales: Ab Ghani, Nur Syatila, Ramlan, Effirul Ikhwan, Firdaus-Raih, Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602481/
https://www.ncbi.nlm.nih.gov/pubmed/31106379
http://dx.doi.org/10.1093/nar/gkz391