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PRECOG: PREdicting COupling probabilities of G-protein coupled receptors

G-protein coupled receptors (GPCRs) control multiple physiological states by transducing a multitude of extracellular stimuli into the cell via coupling to intra-cellular heterotrimeric G-proteins. Deciphering which G-proteins couple to each of the hundreds of GPCRs present in a typical eukaryotic o...

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Detalles Bibliográficos
Autores principales: Singh, Gurdeep, Inoue, Asuka, Gutkind, J Silvio, Russell, Robert B, Raimondi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602504/
https://www.ncbi.nlm.nih.gov/pubmed/31143927
http://dx.doi.org/10.1093/nar/gkz392