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Regulatory functions of the Mediator kinases CDK8 and CDK19

The Mediator-associated kinases CDK8 and CDK19 function in the context of three additional proteins: CCNC and MED12, which activate CDK8/CDK19 kinase function, and MED13, which enables their association with the Mediator complex. The Mediator kinases affect RNA polymerase II (pol II) transcription i...

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Detalles Bibliográficos
Autores principales: Fant, Charli B., Taatjes, Dylan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602567/
https://www.ncbi.nlm.nih.gov/pubmed/30585107
http://dx.doi.org/10.1080/21541264.2018.1556915