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Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition
Nucleoplasmin (NP) is a pentameric histone chaperone that regulates the condensation state of chromatin in different cellular processes. We focus here on the interaction of NP with the histone octamer, showing that NP could bind sequentially the histone components to assemble an octamer-like particl...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602930/ https://www.ncbi.nlm.nih.gov/pubmed/31263230 http://dx.doi.org/10.1038/s41598-019-45726-7 |