His6, His13, and His14 residues in Aβ 1–40 peptide significantly and specifically affect oligomeric equilibria

Oligomers of Aβ peptide are implicated as the most probable causative agent in Alzheimer’s disease. However, their structural properties remain elusive due to the dynamic and heterogeneous character of oligomeric species coexisting in solution. Nevertheless, new approaches, mainly based on mass spec...

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Detalles Bibliográficos
Autores principales: Przygońska, Kaja, Pacewicz, Magdalena, Sadowska, Wiktoria, Poznański, Jarosław, Bal, Wojciech, Dadlez, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602940/
https://www.ncbi.nlm.nih.gov/pubmed/31263161
http://dx.doi.org/10.1038/s41598-019-45988-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602940/
https://www.ncbi.nlm.nih.gov/pubmed/31263161
http://dx.doi.org/10.1038/s41598-019-45988-1

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