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Hypoxia-induced ZEB1 promotes cervical cancer progression via CCL8-dependent tumour-associated macrophage recruitment

The accumulation of tumour-associated macrophages (TAMs) in the hypoxic tumour microenvironment (TME) is associated with malignant progression in cancer. However, the mechanisms by which the hypoxic TME facilitates TAM infiltration are not fully understood. This study showed that high ZEB1 expressio...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Jing, Deng, Yuan-Run, Wang, Zi-Ci, Wei, Wen-Fei, Zhou, Chen-Fei, Zhang, Yan-Mei, Yan, Rui-Ming, Liang, Luo-Jiao, Zhong, Mei, Liang, Li, Wu, Sha, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602971/
https://www.ncbi.nlm.nih.gov/pubmed/31263103
http://dx.doi.org/10.1038/s41419-019-1748-1