HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells

MicroRNAs are dysregulated in breast cancer. Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2/B1) is a reader of the N(6)-methyladenosine (m6A) mark in primary-miRNAs (pri-miRNAs) and promotes DROSHA processing to precursor-miRNAs (pre-miRNAs). We examined the expression of writers, readers, a...

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Detalles Bibliográficos
Autores principales: Klinge, Carolyn M., Piell, Kellianne M., Tooley, Christine Schaner, Rouchka, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603045/
https://www.ncbi.nlm.nih.gov/pubmed/31263129
http://dx.doi.org/10.1038/s41598-019-45636-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603045/
https://www.ncbi.nlm.nih.gov/pubmed/31263129
http://dx.doi.org/10.1038/s41598-019-45636-8

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