Middle Ear Administration of a Particulate Chitosan Gel in an in vivo Model of Cisplatin Ototoxicity

BACKGROUND: Middle ear (intratympanic, IT) administration is a promising therapeutic method as it offers the possibility of achieving high inner ear drug concentrations with low systemic levels, thus minimizing the risk of systemic side effects and drug-drug interactions. Premature elimination throu...

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Detalles Bibliográficos
Autores principales: Videhult Pierre, Pernilla, Fransson, Anette, Kisiel, Marta Alina, Damberg, Peter, Nikkhou Aski, Sahar, Andersson, Mats, Hällgren, Lotta, Laurell, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603134/
https://www.ncbi.nlm.nih.gov/pubmed/31293387
http://dx.doi.org/10.3389/fncel.2019.00268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603134/
https://www.ncbi.nlm.nih.gov/pubmed/31293387
http://dx.doi.org/10.3389/fncel.2019.00268

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