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Diarrheal Etiology and Impact of Coinfections on Rotavirus Vaccine Efficacy Estimates in a Clinical Trial of a Monovalent Human–Bovine (116E) Oral Rotavirus Vaccine, Rotavac, India

BACKGROUND: Rotavirus vaccine efficacy (VE) estimates in low-resource settings are lower than in developed countries. We detected coinfections in cases of severe rotavirus diarrhea in a rotavirus VE trial to determine whether these negatively impacted rotavirus VE estimates. METHODS: We performed Ta...

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Detalles Bibliográficos
Autores principales: Praharaj, Ira, Platts-Mills, James A, Taneja, Sunita, Antony, Kalpana, Yuhas, Krista, Flores, Jorge, Cho, Iksung, Bhandari, Nita, Revathy, R, Bavdekar, Ashish, Rongsen-Chandola, Temsunaro, McMurry, Timothy, Houpt, Eric R, Kang, Gagandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603264/
https://www.ncbi.nlm.nih.gov/pubmed/30335135
http://dx.doi.org/10.1093/cid/ciy896