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Mutations in the Global Transcription Factor CRP/CAP: Insights from Experimental Evolution and Deep Sequencing
The Escherichia coli cyclic AMP receptor protein (CRP or catabolite activator protein, CAP) provides a textbook example of bacterial transcriptional regulation and is one of the best studied transcription factors in biology. For almost five decades a large number of mutants, evolved in vivo or engin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603298/ https://www.ncbi.nlm.nih.gov/pubmed/31303977 http://dx.doi.org/10.1016/j.csbj.2019.05.009 |