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Overexpression of miR-15b Promotes Resistance to Sunitinib in Renal Cell Carcinoma

Aim: Sunitinib remains the frontline treatment for metastatic clear-cell renal cell carcinoma (ccRCC). Drug resistance is inevitable and related mechanism warrant insightful elaboration. Methods: In silico data mining of GEO and TCGA datasets was performed to identify potential target micro-RNA. In...

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Detalles Bibliográficos
Autores principales: Lu, Lu, Li, Yanmin, Wen, Hui, Feng, Chenchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603409/
https://www.ncbi.nlm.nih.gov/pubmed/31293642
http://dx.doi.org/10.7150/jca.31676