Avibactam Sensitizes Carbapenem-Resistant NDM-1–Producing Klebsiella pneumoniae to Innate Immune Clearance

Infections caused by New Delhi metallo-β-lactamase (NDM)–producing strains of multidrug-resistant Klebsiella pneumoniae are a global public health threat lacking reliable therapies. NDM is impervious to all existing β-lactamase inhibitor (BLI) drugs, including the non–β-lactam BLI avibactam (AVI). T...

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Detalles Bibliográficos
Autores principales: Ulloa, Erlinda R, Dillon, Nicholas, Tsunemoto, Hannah, Pogliano, Joe, Sakoulas, George, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603980/
https://www.ncbi.nlm.nih.gov/pubmed/30923801
http://dx.doi.org/10.1093/infdis/jiz128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603980/
https://www.ncbi.nlm.nih.gov/pubmed/30923801
http://dx.doi.org/10.1093/infdis/jiz128

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