Cargando…

Avibactam Sensitizes Carbapenem-Resistant NDM-1–Producing Klebsiella pneumoniae to Innate Immune Clearance

Infections caused by New Delhi metallo-β-lactamase (NDM)–producing strains of multidrug-resistant Klebsiella pneumoniae are a global public health threat lacking reliable therapies. NDM is impervious to all existing β-lactamase inhibitor (BLI) drugs, including the non–β-lactam BLI avibactam (AVI). T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ulloa, Erlinda R, Dillon, Nicholas, Tsunemoto, Hannah, Pogliano, Joe, Sakoulas, George, Nizet, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603980/ https://www.ncbi.nlm.nih.gov/pubmed/30923801 http://dx.doi.org/10.1093/infdis/jiz128

Ejemplares similares

2390. Avibactam Sensitizes NDM Klebsiella pneumoniae to Innate Immune Killing by Human Cathelicidin LL-37, Serum, Neutrophils, and Platelets
por: Ulloa, Erlinda Rose, et al.
Publicado: (2018)

Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens
por: Dillon, Nicholas, et al.
Publicado: (2019)

255. Ticagrelor Aids Platelet-Mediated Clearance in a Refractory Staphylococcus aureus Endovascular Infection with Septic Emboli
por: Ulloa, Erlinda, et al.
Publicado: (2020)

Whole Genome Sequencing of Peruvian Klebsiella pneumoniae Identifies Novel Plasmid Vectors Bearing Carbapenem Resistance Gene NDM-1
por: Roach, David, et al.
Publicado: (2020)

Clinical Characteristics and Outcome of Ceftazidime/Avibactam-Resistant Klebsiella pneumoniae Carbapenemase–Producing Klebsiella pneumoniae Infections: A Retrospective, Observational, 2-Center Clinical Study
por: Oliva, Alessandra, et al.
Publicado: (2023)

Potent Activity of Ertapenem Plus Cefazolin Within Staphylococcal Biofilms: A Contributing Factor in the Treatment of Methicillin-Susceptible Staphylococcus aureus Endocarditis
por: Gilbertie, Jessica, et al.
Publicado: (2022)

An NDM-Producing Escherichia coli Clinical Isolate Exhibiting Resistance to Cefiderocol and the Combination of Ceftazidime-Avibactam and Aztreonam: Another Step Toward Pan-β-Lactam Resistance
por: Simner, Patricia J, et al.
Publicado: (2023)

349 Surveillance of Carbapenem Resistance and the First Case of NDM-7-producing Klebsiella pneumoniae in the Philippines
por: Chou, Andrew, et al.
Publicado: (2014)

NDM-1–producing Klebsiella pneumoniae, Croatia
por: Mazzariol, Annarita, et al.
Publicado: (2012)

Ceftazidime/Avibactam Resistance in Carbapenemase-Producing Klebsiella pneumoniae
por: Cui, Qiaozhen, et al.
Publicado: (2023)

665. Modified Superposition in vitro Susceptibility of Aztreonam and Ceftazidime/Avibactam for an NDM-5 Metallo-β-Lactamase-Producing Klebsiella pneumoniae Isolate
por: Schmetterer, Justin, et al.
Publicado: (2022)

Evaluation of ceftazidime/avibactam for treatment of carbapenemase-producing carbapenem-resistant Enterobacterales with OXA-48 and/or NDM genes with or without combination therapy
por: Alqahtani, Hajar, et al.
Publicado: (2022)

Carbapenem-Resistant Klebsiella pneumoniae in Southwest China: Molecular Characteristics and Risk Factors Caused by KPC and NDM Producers
por: Li, Zhaoyinqian, et al.
Publicado: (2021)

Spread of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Producing NDM-Type Metallo-β-Lactamase in Myanmar
por: Takei, Satomi, et al.
Publicado: (2022)

Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus
por: Salazar, Michael J., et al.
Publicado: (2020)

Antibacterial Activity and Optimal Treatment of Ceftazidime-Avibactam and Aztreonam-Avibactam Against Bloodstream Infections Caused by Carbapenem-Resistant Klebsiella pneumoniae
por: Yu, Wei, et al.
Publicado: (2021)

In vitro Optimization of Ceftazidime/Avibactam for KPC-Producing Klebsiella pneumoniae
por: Huang, Yanqin, et al.
Publicado: (2021)

Emergence of NDM-5 Producing Carbapenem-Resistant Klebsiella aerogenes in a Pediatric Hospital in Shanghai, China
por: Pan, Fen, et al.
Publicado: (2021)

The emergence of carbapenem-resistant Klebsiella pneumoniae isolates producing OXA-48 and NDM in the Southern (Asir) province, Saudi Arabia
por: Al-Zahrani, Ibrahim A., et al.
Publicado: (2018)

Clonal dissemination of carbapenem-resistant Klebsiella pneumoniae ST16 co-producing NDM-1 and OXA-232 in Thailand
por: Abe, Ryuichiro, et al.
Publicado: (2022)

Emergence of Ceftazidime/Avibactam and Tigecycline Resistance in Carbapenem-Resistant Klebsiella pneumoniae Due to In-Host Microevolution
por: Han, Xinhong, et al.
Publicado: (2021)

Carbapenem-Resistant Klebsiella pneumoniae Osteomyelitis Treated with Ceftazidime-Avibactam in an Infant: A Case Report
por: Ji, Zejuan, et al.
Publicado: (2021)

Efficacy of Ceftazidime-Avibactam in the Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infection After Kidney Transplantation
por: Zhang, Fei, et al.
Publicado: (2021)

The Rapid Prediction of Carbapenem Resistance in Patients With Klebsiella pneumoniae Bacteremia Using Electronic Medical Record Data
por: Sullivan, Timothy, et al.
Publicado: (2018)

Regional Spread of bla(NDM-1)-Containing Klebsiella pneumoniae ST147 in Post-Acute Care Facilities
por: Lapp, Zena, et al.
Publicado: (2021)

Emergence of Ceftazidime-Avibactam Resistance and Restoration of Carbapenem Susceptibility in Klebsiella pneumoniae Carbapenemase-Producing K pneumoniae: A Case Report and Review of Literature
por: Shields, Ryan K., et al.
Publicado: (2017)

Bacterial Cytological Profiling (BCP) as a Rapid and Accurate Antimicrobial Susceptibility Testing Method for Staphylococcus aureus
por: Quach, D.T., et al.
Publicado: (2016)

Bacterial cytological profiling reveals interactions between jumbo phage φKZ infection and cell wall active antibiotics in Pseudomonas aeruginosa
por: Tsunemoto, Hannah, et al.
Publicado: (2023)

598. In Vitro Activity of Aztreonam in Combination with Ceftazidime–Avibactam, Amoxicillin–Clavulanate, and Piperacillin–Tazobactam vs. NDM-Producing Escherichia coli and Klebsiella pneumoniae Clinical Isolates
por: Walkty, Andrew, et al.
Publicado: (2019)

Detection of NDM Variants (bla(NDM-1), bla(NDM-2), bla(NDM-3)) from Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae: First Report from Nepal
por: Thapa, Anisha, et al.
Publicado: (2022)

2451. Synergistic Activity of Ceftazidime–Avibactam in Combination With Polymyxin B Against Carbapenem-Resistant Klebsiella pneumoniae
por: Borjan, Jovan, et al.
Publicado: (2018)

Ceftazidime-Avibactam as Salvage Treatment for Infections Due to Carbapenem-Resistant Klebsiella pneumoniae in Liver Transplantation Recipients
por: Chen, Fang, et al.
Publicado: (2021)

Derivation of a Model to Guide Empiric Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infection in an Endemic Area
por: Weston, Gregory, et al.
Publicado: (2020)

Changing Epidemiology of Carbapenemases Among Carbapenem-Resistant Enterobacterales From United States Hospitals and the Activity of Aztreonam-Avibactam Against Contemporary Enterobacterales (2019–2021)
por: Sader, Helio S, et al.
Publicado: (2023)

In vitro evaluation of double carbapenem and colistin combinations against OXA-48, NDM carbapenemase-producing colistin-resistant Klebsiella pneumoniae strains
por: Erdem, Fatma, et al.
Publicado: (2020)

Whole genome sequencing characterization of Slovenian carbapenem-resistant Klebsiella pneumoniae, including OXA-48 and NDM-1 producing outbreak isolates
por: Benulič, Katarina, et al.
Publicado: (2020)

Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48- and NDM-Producing Escherichia coli and Klebsiella pneumoniae
por: Allander, Lisa, et al.
Publicado: (2022)

Carbapenem-Resistant Klebsiella pneumoniae Infection in Three New York City Hospitals Trended Downwards From 2006 to 2014
por: Park, Sun O., et al.
Publicado: (2016)

NDM-1 and rmtC-Producing Klebsiella pneumoniae Isolates in Turkey
por: Guven Gokmen, Tulin, et al.
Publicado: (2016)

173. Successful Treatment of Carbapenem-Resistant Klebsiella pneumoniae (CR-Kp) Aortic Valve Endocarditis with Ceftazidime–Avibactam
por: Alegro, Jason V, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_acs8pj72aa5q7m7s7av5831bjh